This version (2024/07/08 12:31) was approved by grahamw.

Hull University Teaching Hospitals NHS Trust - Nuclear Medicine

Uncontrolled if printed

SOP CodeTitleReview Date
REF006Cardiac Amyloidosis Imaging Referral Criteria2027-07-08


Authorised By Authorising Role Authorisation Signature
(only on master paper copy)
Date Authorised
Dr I Sunderji ARSAC Licence Holder 2024-07-08

REF006 - Cardiac Amyloidosis Imaging Referral Criteria

See REF000 - Referring to Nuclear Medicine (HUTH) for details of how to refer.

Description

Myocardial uptake of the radiotracer Technetium-99m-DPD has been validated and increasingly used in the non-biopsy diagnostic pathway of transthyretin related cardiac amyloidosis (ATTR). It offers a highly sensitive tool for detecting this disease and plays a key role in the non-invasive diagnostic workup of these patients[1]. However, it should be noted that DPD imaging is neither a primary tool to diagnose amyloid cardiomyopathy nor a tool to exclude cardiac amyloidosis on its own.

ARSAC Licence HoldersIndication
Prof Stephen Richard Underwoodcardiac amyloid imaging
Dr Imran Sunderjicardiac amyloid imaging


Radiopharmaceutical CT component of SPECT/CT
Typical Radiation Dose (mSv) 5.6 0.5

Staff Entitled to Refer

All UK registered practitioners

Supplementary Drugs

Sodium chloride for parenteral use (0.9% w/v).

Contraindications

Pregnancy

Clinical Indications

Clinical suspicion of amyloid involving the heart[1][2]
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